CafÃ©–au–lait spots are smooth, often irregular, brown spots on the skin.. 0.3% of Caucasian 0.4% of Chinese 3% of Hispanic 18% of African American.. than six cafÃ©–au–lait spots at the age of 5 or a large cafÃ©–au–lait spot, you should show it .
Other syndromes definitely associated with multiple cafe–au–lait macules include: (1) neurofibromatosis type 2 (NF2); (2) Legius syndrome (NF1-like syndrome); (3) autosomal dominant multiple cafe–au–lait macules; (4) Watson syndrome; (5) McCune-Albright syndrome; (6) LEOPARD syndrome; (7) ring chromosome syndromes; and.
Define cafÃ© au lait spots typical of neurofibromatosis type 1 (NF1) and describe. The giant melanosomes in CAL spots are not unique to NF1; they can be seen in. The frequency of having at least one CAL spot has been reported as 3% in .
These resemble cafÃ©–au–lait spots (1â€“3 mm in diameter) and develop after the. (